Selank Protocol
Dosing & Research
Last Updated: April 22, 2026
Anxiolytic and stress research, Immune-neuro interface studies, Cognition/focus models, Nasal peptide delivery
Evidence Level
Human Clinical Data Available
Species Studied
Human • Rat • Mouse
Half-Life
Minutes (plasma); extended CNS activity
Administration
• Intranasal
• Subcutaneous
Frequency
Daily or 3-5x weekly
How It Works
- Anxiolytic and stress research
- Immune-neuro interface studies
- Cognition/focus models
- Nasal peptide delivery
Dosing Structure
Dose
200–500 mcg
Frequency
Daily or 3-5x weekly
Notes
Daily SubQ: 100-300mcg. 3x-5x per week SubQ: 200-500mcg (some protocols call for a max of 1mg per day). Intranasal: 750mcg-1mg. Cycle Durations: Daily: 1 month on, 1 month off. 3-5x per week: 2 months on, 2 months off. Inject: Abdomen, thigh, or upper arm. Morning for cognitive, evening for anxiety. Break: 1-2 weeks (optional).
Example Protocols
Dose: 200–500 mcg
Frequency: Daily or 3-5x weekly
Duration: 8 Weeks
Off Period: Not listed
Protocol Notes
•
Daily SubQ: 100-300mcg.
•
3x-5x per week SubQ: 200-500mcg (some protocols call for a max of 1mg per day).
•
Intranasal: 750mcg-1mg.
•
Cycle Durations: Daily: 1 month on, 1 month off.
•
3-5x per week: 2 months on, 2 months off.
•
Inject: Abdomen, thigh, or upper arm.
•
Morning for cognitive, evening for anxiety.
•
Break: 1-2 weeks (optional).
Research & Studies
Loading citations…
- Curated References
- CuratedPubMedPMID 19718432Selank in the treatment of generalized anxiety disorder↗Bull Exp Biol Med · 2009 · Semenova TP, Kozlovskaya MM, Gerasimova VS.humandosinganxietyclinical
- CuratedPubMedPMID 24737265Selank modulates the expression of genes related to the immune response↗Peptides · 2014 · Ershov FI, Narovlyansky AN, Mezentseva MV.immunemechanismanimal
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