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Metabolic

Survodutide Protocol

Dosing & Research

Last Updated: August 30, 2026

Chemical Identity
Molecular Formula
C192H289N47O61
Molecular Weight
4231.69 g/mol
CAS Number
2805997-46-8

Obesity/NAFLD research, GLP-1/glucagon dual agonism, Liver-fat reduction studies, Weight-management trials

Half-Life
Long-acting; supports once-weekly dosing
Administration
Subcutaneous
Frequency
Once Or Twice Weekly, Same Day(s) Each Week

How It Works

  • Obesity/NAFLD research
  • GLP-1/glucagon dual agonism
  • Liver-fat reduction studies
  • Weight-management trials

Dosing Structure

Dose
0.3mg-6mg weekly (titrated)
Frequency
Once Or Twice Weekly, Same Day(s) Each Week
Notes
1x Weekly titration: Week 1-4: 0.3mg | Week 5-8: 0.6mg | Week 9-12: 1.2mg | Week 13-16: 2.4mg | Week 17-20: 3.6mg | Week 21-24: 4.8mg | Week 25+: 6mg. 2x Weekly titration: Week 1-4: 0.15mg | Week 5-8: 0.3mg | Week 9-12: 0.6mg | Week 13-16: 1.2mg | Week 17-20: 1.8mg | Week 21-24: 2.4mg | Week 25+: 3mg. No need to increase dose if experiencing benefits. Inject: Abdomen (2+ inches from navel), upper thigh, or upper arm. Any time of day with or without food. Typically follows a weekly titration schedule.

Example Protocols

Dose: 0.3mg-6mg weekly (titrated)
Frequency: Once Or Twice Weekly, Same Day(s) Each Week
Duration: Long-term Continuous Weekly Treatment
Off Period: Not listed
Calculate dosing →

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Protocol Notes

1x Weekly titration
Week 1-4: 0.3mgWeek 5-8: 0.6mgWeek 9-12: 1.2mgWeek 13-16: 2.4mgWeek 17-20: 3.6mgWeek 21-24: 4.8mgWeek 25+: 6mg
2x Weekly titration
Week 1-4: 0.15mgWeek 5-8: 0.3mgWeek 9-12: 0.6mgWeek 13-16: 1.2mgWeek 17-20: 1.8mgWeek 21-24: 2.4mgWeek 25+: 3mg
No need to increase dose if experiencing benefits.
Inject: Abdomen (2+ inches from navel), upper thigh, or upper arm.
Any time of day with or without food.
Typically follows a weekly titration schedule.

Research & Studies

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