MGF Protocol
Dosing & Research
Last Updated: April 22, 2026
Also known as: Mechano Growth Factor, IGF-1Ec, IGF-1 Splice Variant
Muscle hypertrophy research, Mechanical load adaptation, Satellite cell activation, Injury-induced repair, Skeletal muscle remodeling
Half-Life
Mechanosensitive Splice Variant Of IGF-1 Produced By Muscle In Response To Mechanical Loading. Exhibits Local Paracrine Effects On Satellite Cells.
Administration
Subcutaneous
Frequency
Variable
How It Works
- Local intramuscular application. Activates PI3K-Akt and MAPK signaling for myotube fusion.
- Muscle hypertrophy research
- Mechanical load adaptation
- Satellite cell activation
- Injury-induced repair
Dosing Structure
Dose
100–200 mcg per injection (local)
Frequency
Variable
Example Protocols
Dose: 100–200 mcg per injection (local)
Frequency: Variable
Duration: ~1–2 Hours
Off Period: Not listed
Research & Studies
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