MGF Protocol

Dosing & Research

Last Updated: September 4, 2026

Also known as: Mechano Growth Factor, IGF-1Ec, IGF-1 Splice Variant

Muscle hypertrophy research, Mechanical load adaptation, Satellite cell activation, Injury-induced repair, Skeletal muscle remodeling

Half-Life

~1–2 Hours

Administration

Subcutaneous

Frequency

Variable

How It Works

Mechanosensitive splice variant of IGF-1 produced by muscle in response to mechanical loading. Exhibits local paracrine effects on satellite cells.
Muscle hypertrophy research
Mechanical load adaptation
Satellite cell activation
Injury-induced repair

Dose

100–200 mcg per injection (local)

Frequency

Variable

Notes

Local Intramuscular Application. Activates PI3K-Akt And Mapk Signaling For Myotube Fusion.

Dose: 100–200 mcg per injection (local)

Frequency: Variable

Duration: Not listed

Off Period: Not listed

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Third-party COA-verified research peptides with published batch testing.

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Local intramuscular application.

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Activates PI3K-Akt and MAPK signaling for myotube fusion.

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