Tesamorelin Protocol
Dosing & Research
Last Updated: April 22, 2026
HIV-associated lipodystrophy research, Visceral-fat reduction, GH axis studies, NAFLD and body-composition research
Evidence Level
Human Clinical Data Available
Species Studied
Human • Rat
Half-Life
26-38 minutes
Administration
Subcutaneous
Frequency
Once Daily, 90 Minutes After Last Meal, Before Bed
How It Works
- HIV-associated lipodystrophy research
- Visceral-fat reduction
- GH axis studies
- NAFLD and body-composition research
Dosing Structure
Dose
1 mg daily
Frequency
Once Daily, 90 Minutes After Last Meal, Before Bed
Notes
Standard: 1mg taken 90 minutes after last meal, before bed. Aggressive: 2mg taken 90 minutes after last meal, before bed. If on a GLP-1, consider taking dose first thing in the morning as GLP-1 delays fasted state by many hours. Inject: Abdomen (avoid navel ±2 inches), rotate sites. Break: 1-2 months.
Example Protocols
Dose: 1 mg daily
Frequency: Once Daily, 90 Minutes After Last Meal, Before Bed
Duration: 6-12 weeks
Off Period: Not listed
Protocol Notes
•
Standard: 1mg taken 90 minutes after last meal, before bed.
•
Aggressive: 2mg taken 90 minutes after last meal, before bed.
•
If on a GLP-1, consider taking dose first thing in the morning as GLP-1 delays fasted state by many hours.
•
Inject: Abdomen (avoid navel ±2 inches), rotate sites.
•
Break: 1-2 months.
Research & Studies
Loading citations…
- Curated References
- CuratedPubMedPMID 20357282Effects of growth hormone-releasing factor on abdominal fat in HIV-infected patients with fat accumulation↗N Engl J Med · 2010 · Falutz J, Mamputu JC, Potvin D, et al.dosinghumanphase-3visceral fat
- CuratedPubMedPMID 27749059Tesamorelin effect on functional outcomes in older adults with MCI↗JAMA Neurol · 2016 · Friedman SD, Baker LD, Borson S, et al.humancognitivedosingMCI
- CuratedPubMedPMID 29505025Tesamorelin reduces liver fat in HIV-infected patients with NAFLD↗J Hepatol · 2019 · Stanley TL, Fourman LT, Feldpausch MN, et al.humanNASHliverdosing
Research Feedback
0 approved
For research discussion only. Community feedback is moderated and shown here as aggregated insights after approval.
Be the first to submit research feedback for this peptide.
Approved submissions will appear here as aggregated insights.