Sermorelin Protocol
Dosing & Research
Last Updated: April 22, 2026
GH deficiency testing/support, IGF-1 axis modulation, Body-composition research, Recovery and sleep studies
Evidence Level
Human Clinical Data Available
Species Studied
Human • Rat
Half-Life
Approximately 10-20 minutes
Administration
Subcutaneous
Frequency
Once Daily, 2 Hours After Last Meal
How It Works
- GH deficiency testing/support
- IGF-1 axis modulation
- Body-composition research
- Recovery and sleep studies
Dosing Structure
Dose
200–250 mcg
Frequency
Once Daily, 2 Hours After Last Meal
Notes
1x Daily: 200–500mcg taken 2 hours after last meal (once daily). IM is also effective. Inject: Lower abdomen, anterior thigh, posterior upper arm (rotate). Administer at least 2 hours after last meal. Break: 1-2 months or 5 days on/2 days off.
Example Protocols
Dose: 200–250 mcg
Frequency: Once Daily, 2 Hours After Last Meal
Duration: 6-12 weeks
Off Period: Not listed
Protocol Notes
•
1x Daily: 200–500mcg taken 2 hours after last meal (once daily).
•
IM is also effective.
•
Inject: Lower abdomen, anterior thigh, posterior upper arm (rotate).
•
Administer at least 2 hours after last meal.
•
Break: 1-2 months or 5 days on/2 days off.
Research & Studies
Loading citations…
- Curated References
- CuratedPubMedPMID 7768356Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency↗Drugs · 1990 · Walker RF.humanGHdiagnosticdosing
- CuratedPubMedPMID 1987230Growth hormone-releasing hormone stimulation test in adults↗J Clin Endocrinol Metab · 1996 · Ghigo E, Aimaretti G, Gianotti L, et al.humanGHdiagnosticdosing
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