Epithalon Protocol
Dosing & Research
Last Updated: April 22, 2026
Telomerase and cellular aging studies, Circadian regulation, Oxidative-stress resilience, Geroprotection research
Evidence Level
In Vitro / Preclinical
Species Studied
Human • Rat • Mouse • In vitro
Half-Life
~30 Minutes
Administration
Subcutaneous
Frequency
Daily For 10 Days, Or Every 3 Days For 17 Days
How It Works
- Telomerase and cellular aging studies
- Circadian regulation
- Oxidative-stress resilience
- Geroprotection research
Dosing Structure
Dose
2 mg nightly
Frequency
Daily For 10 Days, Or Every 3 Days For 17 Days
Notes
Russian Protocol: 10mg per day for 10 days. 4-6 months break recommended. Ukrainian Protocol: 10mg every 3 days for 17 days. 4-6 months break recommended. Anela Protocol: 1mg per day for 10 days on, 20 days off. This 30-day cycle is reportedly repeatable. Typically administered as defined courses (10–20 days) repeated 1–2x per year, rather than continuous daily dosing. Based on Khavinson Institute and associated Russian clinical research. Inject: Abdomen, thigh, or upper arm. Morning preferred.
Example Protocols
Dose: 2 mg nightly
Frequency: Daily For 10 Days, Or Every 3 Days For 17 Days
Duration: 20 Days (repeat Cycles)
Off Period: Not listed
Protocol Notes
•
Russian Protocol: 10mg per day for 10 days.
•
4-6 months break recommended.
•
Ukrainian Protocol: 10mg every 3 days for 17 days.
•
4-6 months break recommended.
•
Anela Protocol: 1mg per day for 10 days on, 20 days off.
•
This 30-day cycle is reportedly repeatable.
•
Typically administered as defined courses (10–20 days) repeated 1–2x per year, rather than continuous daily dosing.
•
Based on Khavinson Institute and associated Russian clinical research.
•
Inject: Abdomen, thigh, or upper arm.
•
Morning preferred.
Research & Studies
Loading citations…
- Curated References
- CuratedPubMedPMID 12374906Peptide Epitalon activates telomerase in somatic cells↗Bull Exp Biol Med · 2003 · Khavinson VKh, Bondarev IE, Butyugov AA.mechanismtelomerasein vitro
- CuratedPubMedPMID 12802523Peptide Epitalon increases lifespan of Drosophila↗Mech Ageing Dev · 2000 · Khavinson V, Razumovsky M, Trofimova S, et al.longevityanimal
- CuratedPubMedPMID 22349875Epithalon normalizes melatonin production in pinealectomized rats↗Neuro Endocrinol Lett · 2010 · Anisimov VN, Khavinson VK.melatoninanimaldosing
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