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HMG Protocol

Dosing & Research

Last Updated: September 4, 2026

Also known as: Human Menopausal Gonadotropin, Menotropin, Pergonal

Gonadal stimulation, Fertility and ovulation research, Steroidogenesis investigation, Spermatogenesis studies

Half-Life

24–40 Hours

Administration

Subcutaneous

Frequency

Variable

How It Works

Extracted gonadotropin mixture from postmenopausal urine (FSH and LH ~1:1 ratio). Stimulates steroidogenesis and gametogenesis.
Gonadal stimulation
Fertility and ovulation research
Steroidogenesis investigation
Spermatogenesis studies

Dosing Structure

Dose

7.5–30 mcg FSH/LH per injection (equivalent to 75–300 IU)

Frequency

Variable

Notes

Typical 7–12 day stimulation cycles. FSH acts on granulosa/Sertoli cells; LH acts on theca/Leydig cells. Conversion varies by assay: approximately 0.1 mcg per IU.

Example Protocols

Dose: 7.5–30 mcg FSH/LH per injection (equivalent to 75–300 IU)

Frequency: Variable

Duration: Not listed

Off Period: Not listed

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Protocol Notes

•

Typical 7–12 day stimulation cycles.

•

FSH acts on granulosa/Sertoli cells; LH acts on theca/Leydig cells.

•

Conversion varies by assay: approximately 0.1 mcg per IU.

Research & Studies

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