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Immune Modulation

KPV Protocol

Dosing & Research

Last Updated: September 4, 2026

Chemical Identity
Amino Acid Sequence
Lys-Pro-Val
Molecular Formula
C16H30N4O4
Molecular Weight
342.44 g/mol
CAS Number
67727-97-3

Gut inflammation models, Dermatology/topical studies, Antimicrobial peptide research, IBD-related signaling

Half-Life
Often cited around 1-2 hours; human PK data limited
Administration
• Oral • Subcutaneous
Frequency
Once Daily (subq) Or Twice Daily (oral)

How It Works

  • Gut inflammation models
  • Dermatology/topical studies
  • Antimicrobial peptide research
  • IBD-related signaling

Dosing Structure

Dose
250–500 mcg
Frequency
Once Daily (subq) Or Twice Daily (oral)
Notes
SubQ Dosing: 200-400mcg per day. Oral Dosing: 250mcg twice daily. Cycling KPV is not strictly required; however, it is recommended to reassess needs every 30 days. Inject: Abdomen (preferred for gut issues), thigh, upper arm. Break: 2-4 weeks to assess baseline.

Example Protocols

Dose: 250–500 mcg
Frequency: Once Daily (subq) Or Twice Daily (oral)
Duration: 8 Weeks
Off Period: Not listed
Calculate dosing →

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Protocol Notes

SubQ Dosing: 200-400mcg per day.
Oral Dosing: 250mcg twice daily.
Cycling KPV is not strictly required; however, it is recommended to reassess needs every 30 days.
Inject: Abdomen (preferred for gut issues), thigh, upper arm.
Break: 2-4 weeks to assess baseline.

Research & Studies

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